Background:

Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Applications:

WB

Name of antibody:

ME3

Immunogen:

Synthesized peptide derived from internal of human ME3.

Full name:

malic enzyme 3, NADP(+)-dependent, mitochondrial

Synonyms：

NADP-ME

SwissProt:

Q16798

WB Predicted band size:

67 kDa

WB Positive control:

NIH/3T3 cells and RAW264.7 cells lysates

WB Recommended dilution:

500-3000